Informational Macromolecules

in Wilson's disease, and localization of iron in hemochromatosis. On pages 2 and 166, Birks discussed future trends in electron probe mocroanalysis, including lower cost instruments and those that will quantitate elements down to carbon. Such developments would open this microanalytic technique to the realm of the biologist. Birks writes with a crisp style, and with the insight of a worker in the field (there are 15 citations after his name in the author index). A brief subject index and an appendix add to the value of the eleven chapters. Several of the illustrations would be enhanced by the labelling of axes and parts (Fig. 2-8, 2-9, 2-11). A random check of several of the references listed at the end of each chapter did not disclose any errors. Birks has presented a volume (one in a series of monographs dealing with analytic chemistry) that will serve as an admirable introduction to electron probe microanalysis.